Description

Ac-Arg-Ome Hcl is a protected arginine derivative, specifically the hydrochloride salt of Nα-Acetyl-L-arginine methyl ester. This high-purity building block is critical for peptide synthesis and biochemical research, offering precise control over molecular structure. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions engaged in developing novel therapeutic peptides and studying protein-protein interactions.

Application

• Peptide Synthesis: Serves as a key protected intermediate in solid-phase and solution-phase peptide synthesis (SPPS) for incorporating arginine residues.
• Pharmaceutical Research: Used in the development and scale-up of peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Bioconjugation: Acts as a reagent for modifying peptides and proteins, leveraging the reactive guanidino group of arginine after deprotection.
• Biochemical Studies: Employed as a substrate or inhibitor analog in enzymatic studies, particularly those involving trypsin-like proteases.
• Standards and Reference Materials: Provides a high-purity standard for analytical method development and quality control in peptide manufacturing.

Basic Information

Product Name	Ac-Arg-Ome Hcl
CAS No.	1784-05-0
Molecular Formula	C9H19N5O3 • HCl
Molecular Weight	281.74 g/mol (Free base: 245.28)
Synonyms	Nα-Acetyl-L-arginine methyl ester hydrochloride; Ac-L-Arg-OMe • HCl; N-Acetyl-L-arginine methyl ester HCl; Methyl N2-acetyl-L-argininate hydrochloride; L-Arginine, N2-acetyl-, methyl ester, hydrochloride; Ac-Arg-OMe•HCl; Ac-Arg-OMe hydrochloride; N-Acetylarginine methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our Ac-Arg-Ome Hcl is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, optical rotation, and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for research and pharmaceutical applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]	Contact for details
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.