Description

H-Ser-Obzl Hcl CAS NO 1738-72-3 is a protected serine derivative, specifically the hydrochloride salt of O-benzyl-L-serine, widely utilized as a key chiral building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring high-purity intermediates for the construction of complex peptides and peptidomimetics. It is particularly valuable for the pharmaceutical, biotechnology, and agrochemical industries, where precise stereochemistry and reliable quality are paramount for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon in the research and development of novel therapeutic peptides, protease inhibitors, and other bioactive molecules.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) where the benzyl (Bzl) group protects the serine side chain hydroxyl during coupling reactions.
• Chemical Biology Research: Serves as a building block for creating custom amino acid analogs and probes to study protein function and enzyme mechanisms.
• Agrochemical Development: Employed in the synthesis of specialized amino acid-based compounds with potential herbicidal or insecticidal activity.
• Material Science: Can be incorporated into specialized polymers or dendrimers that require amino acid functionality for specific material properties.

Basic Information

Product Name	H-Ser-Obzl Hcl
CAS No.	1738-72-3
Molecular Formula	C10H14ClNO3
Molecular Weight	231.68 g/mol
Synonyms	O-Benzyl-L-serine hydrochloride; L-Serine, O-benzyl-, hydrochloride; H-Ser(Bzl)-OH·HCl; (S)-2-Amino-3-(benzyloxy)propanoic acid hydrochloride; Serine, O-benzyl-, hydrochloride, L-; Benzyl L-serinate hydrochloride; NSC 3349; Fmoc-Ser(Bzl)-OH precursor
EINECS	217-085-2

Quality Control

Every batch of H-Ser-Obzl Hcl is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as assay, chiral purity, and impurity profiles. Our quality commitment supports compliance with cGMP guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.