Description

4'-(Trifluoromethoxy)Acetanilide is a specialized organic intermediate featuring a trifluoromethoxy-substituted aniline core. This compound is valued for its role in introducing the metabolically stable and lipophilic trifluoromethoxy group into target molecules, which is a key strategy in modern pharmaceutical and agrochemical design. It is primarily sought by research and development chemists in the pharmaceutical industry for the synthesis of novel active ingredients, as well as by agrochemical manufacturers developing advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for advanced polymers and liquid crystals, where its unique electronic properties can be leveraged.
• Chemical Biology Probes: Employed in the creation of labeled compounds and probes for studying biological mechanisms and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical suppliers and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	4'-(Trifluoromethoxy)Acetanilide
CAS No.	1737-06-0
Molecular Formula	C9H8F3NO2
Molecular Weight	219.16 g/mol
Synonyms	N-[4-(Trifluoromethoxy)phenyl]acetamide; 4-Acetamidophenyl trifluoromethyl ether; 1-Acetyl-4-(trifluoromethoxy)benzene; 4-(Trifluoromethoxy)acetanilide; p-(Trifluoromethoxy)acetanilide; 4-Acetamidophenyl trifluoromethyl ether; Acetamide, N-[4-(trifluoromethoxy)phenyl]-
EINECS	Contact for details

Quality Control

Our 4'-(Trifluoromethoxy)Acetanilide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.