Description

Dl-Laudanosine CAS NO 1699-51-0 is a benzylisoquinoline alkaloid, a racemic mixture of the D- and L- forms of laudanosine. This compound serves as a critical intermediate and reference standard in pharmaceutical research and development, particularly in the study of neuromuscular blocking agents and their metabolites. It is essential for researchers and manufacturers in the pharmaceutical, analytical chemistry, and life science sectors who require high-purity chemical building blocks for synthesis, method validation, and toxicological studies.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and production of opioid alkaloids and related pharmaceutical compounds.
• Analytical Reference Standard: Used as a certified reference material (CRM) in HPLC, GC-MS, and other chromatographic methods for qualitative and quantitative analysis.
• Metabolite Studies: Employed in pharmacological and toxicological research to study the metabolism of neuromuscular blocking agents like atracurium and cisatracurium.
• Biochemical Research: Utilized as a tool compound in neuroscience to investigate its activity on neuronal nicotinic acetylcholine receptors.
• Chemical Synthesis: Acts as a versatile building block for the organic synthesis of more complex benzylisoquinoline derivatives.
• Quality Control: Serves as an impurity standard in the quality assurance testing of pharmaceutical active ingredients.

Basic Information

Product Name	Dl-Laudanosine
CAS No.	1699-51-0
Molecular Formula	C21H27NO4
Molecular Weight	357.45 g/mol
Synonyms	DL-Laudanosine; (±)-Laudanosine; Laudanosine Racemate; 6,7-Dimethoxy-1-veratryl-1,2,3,4-tetrahydroisoquinoline; 1-[(3,4-Dimethoxyphenyl)methyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline; NSC 143491; Tetrahydro-6,7-dimethoxy-1-veratrylisoquinoline
EINECS	Contact for details

Quality Control

Our Dl-Laudanosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification (IR, NMR), purity assay (HPLC), and control of related substances, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.