Description

α-Cyano-4-Hydroxy-3,5-Diiodobenzyl Acetate is a specialized iodinated aromatic ester with a cyano functional group, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure makes it a valuable precursor for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and high-performance materials. This compound is essential for research and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific iodine-containing motifs into their target compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel iodinated drug candidates, including potential thyroid hormone analogs and X-ray contrast agents.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides that require halogenated aromatic cores for enhanced bioactivity.
• Material Science Research: Acts as a monomer or functionalizing agent in the creation of specialty polymers and liquid crystals where iodine atoms contribute to specific optical or electronic properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for imaging and diagnostic applications, leveraging the heavy atom effect of iodine.
• Organic Synthesis Reagent: Serves as a versatile reagent in cross-coupling reactions and other catalytic transformations to introduce the diiodophenol acetate moiety.

Basic Information

Item	Details
Product Name	α-Cyano-4-Hydroxy-3,5-Diiodobenzyl Acetate
CAS No.	1689-85-6
Molecular Formula	C10H7I2NO3
Molecular Weight	458.98 g/mol
Synonyms	4-Hydroxy-3,5-diiodobenzyl cyanide acetate; 3,5-Diiodo-4-hydroxybenzyl cyanide acetate; (3,5-Diiodo-4-hydroxyphenyl)(cyano)methyl acetate; Acetic acid 2-cyano-2-(3,5-diiodo-4-hydroxyphenyl)ethyl ester; 2-Cyano-2-(3,5-diiodo-4-hydroxyphenyl)ethyl acetate; α-Cyano-3,5-diiodo-4-hydroxybenzyl acetate
EINECS	Contact for details

Quality Control

Our α-Cyano-4-Hydroxy-3,5-Diiodobenzyl Acetate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP-grade requirements. Custom purity specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.