Description

Boc-L-Aspartic Acid 4-tert-Butyl Ester is a high-purity, protected amino acid derivative essential for advanced organic synthesis. This compound is a critical building block in the production of peptides and peptidomimetics, offering precise control over molecular structure. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and development, particularly for creating therapeutic peptides and bioactive molecules. Its reliable quality ensures consistent results in sensitive synthetic pathways.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of aspartic acid into peptide chains while protecting the β-carboxyl group.
• Pharmaceutical Intermediates: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs) for various therapeutic areas.
• Bioconjugation and Labeling: Used in the preparation of modified peptides for diagnostic probes, drug delivery systems, and biochemical studies.
• Research & Development: An indispensable reagent in academic and industrial labs for exploring new peptide-based compounds and their structure-activity relationships.
• Combinatorial Chemistry: Employed in the generation of diverse peptide libraries for high-throughput screening in drug discovery campaigns.

Basic Information

Product Name	Boc-L-Aspartic Acid 4-tert-Butyl Ester
CAS No.	1676-90-0
Molecular Formula	C13H23NO6
Molecular Weight	289.32 g/mol
Synonyms	Boc-Asp(OtBu)-OH; (2S)-2-[(tert-Butoxycarbonyl)amino]butanedioic acid 4-tert-butyl ester; N-(tert-Butoxycarbonyl)-L-aspartic acid 4-tert-butyl ester; Boc-L-Asp(OtBu)-OH; N-Boc-L-aspartic acid 4-tert-butyl ester; L-Aspartic acid, N-[(1,1-dimethylethoxy)carbonyl]-, 4-(1,1-dimethylethyl) ester; Boc-Asp(OtBu)-OH
EINECS	Contact for details

Quality Control

Our Boc-L-Aspartic Acid 4-tert-Butyl Ester is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for pharmaceutical research and synthesis. A Certificate of Analysis (COA) detailing identity, purity, and specific impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider storage under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.5%
Optical Rotation [α]20/D	-20.0° to -24.0° (c=1 in AcOH)
Chiral Purity (HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.