Description

Chlorpromazine n-Oxide is a key pharmaceutical intermediate and metabolite of the antipsychotic drug chlorpromazine. This compound is of significant importance for research and development in neuropharmacology and drug metabolism studies. It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and academic institutions engaged in neuroscience and analytical chemistry.

Application

• Pharmaceutical Intermediate: Critical synthesis component for neuroleptic and antipsychotic drug research.
• Metabolite Reference Standard: Used as an analytical standard in bioanalytical studies to identify and quantify drug metabolites in biological matrices.
• Pharmacological Research: Employed in studies investigating the metabolic pathways, mechanisms of action, and side-effect profiles of phenothiazine-derived drugs.
• Quality Control & Method Development: Serves as a certified reference material (CRM) for developing and validating HPLC, LC-MS, and other analytical methods in pharmaceutical QC labs.
• Biochemical Research: Used in enzymatic and receptor-binding assays to study the interaction of chlorpromazine derivatives.

Basic Information

Product Name	Chlorpromazine n-Oxide
CAS No.	1672-76-0
Molecular Formula	C₁₇H₁₉ClN₂OS
Molecular Weight	334.86 g/mol
Synonyms	Chlorpromazine N-Oxide; Chlorpromazine Sulfoxide; 2-Chloro-10-[3-(dimethylamino)propyl]phenothiazine 5-Oxide; 3-(2-Chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine 5-Oxide; CPZ N-Oxide; Chlorpromazine S-Oxide; Thorazine N-Oxide; Largactil Metabolite
EINECS	Contact for details

Quality Control

Our Chlorpromazine n-Oxide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for research and reference standard applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Chlorpromazine (HPLC)	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.