Description

4',5'-Difluoro-2'-Nitroacetanilide is a high-purity fluorinated aromatic intermediate of significant importance in advanced organic synthesis. Its core value lies in its role as a key building block for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers engaged in the synthesis of active pharmaceutical ingredients (APIs), specialty dyes, and advanced materials, where the introduction of fluorine atoms and nitro groups is strategically required.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel drug candidates, especially those targeting specific biological pathways where fluorinated aromatic rings enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and pesticides, leveraging the fluorine substituents to improve efficacy and environmental profile.
• Dye and Pigment Manufacturing: Serves as a specialized intermediate for producing high-performance, light-fast fluorinated dyes and organic pigments.
• Material Science Research: Employed in the development of organic electronic materials, such as semiconductors for OLEDs, where its molecular structure can be incorporated into conjugated systems.
• Chemical Research & Development: A versatile starting material for academic and industrial R&D focused on nucleophilic aromatic substitution reactions and the construction of complex heterocycles.

Basic Information

Product Name	4',5'-Difluoro-2'-Nitroacetanilide
CAS No.	1662-21-1
Molecular Formula	C8H6F2N2O3
Molecular Weight	216.14 g/mol
Synonyms	N-(2-Nitro-4,5-difluorophenyl)acetamide; 2-Nitro-4,5-difluoroacetanilide; 4,5-Difluoro-2-nitroacetanilide; Acetamide, N-(2-nitro-4,5-difluorophenyl)-; 1-Acetamido-2-nitro-4,5-difluorobenzene; 2'-Nitro-4',5'-difluoroacetanilide; 4,5-Difluoro-2-nitro-N-phenylacetamide
EINECS	Contact for details

Quality Control

Our 4',5'-Difluoro-2'-Nitroacetanilide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.