Description

2,3,3,3-Tetrafluoropropionamide is a specialized fluorinated organic compound that serves as a versatile building block in advanced chemical synthesis. Its unique structure, featuring a high fluorine content adjacent to an amide group, makes it a critical intermediate for introducing fluorinated motifs into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients with enhanced properties such as metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the fluorine atoms contribute to improved lipophilicity and environmental persistence.
• Liquid Crystal Materials: Serves as a building block for fluorinated components in liquid crystal displays (LCDs), enhancing dielectric anisotropy and thermal stability.
• Organic Electronics: Employed in the research and production of materials for organic light-emitting diodes (OLEDs) and semiconductors, leveraging its electron-withdrawing characteristics.
• Fluorinated Polymer Modifier: Acts as a monomer or modifier to impart oil, water, and stain resistance to specialty polymers and surface coatings.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new fluorination methodologies and creating novel fluorinated compounds.

Basic Information

Product Name	2,3,3,3-Tetrafluoropropionamide
CAS No.	1647-57-0
Molecular Formula	C3H3F4NO
Molecular Weight	145.06 g/mol
Synonyms	2,3,3,3-Tetrafluoropropanamide; Tetrafluoropropionamide; 2,3,3,3-Tetrafluoropropionic acid amide; Perfluoropropionamide (incorrect but common); TFPAmide; 1647-57-0; NSC 92366; α,α,β,β-Tetrafluoropropionamide
EINECS	Contact for details

Quality Control

Our production of 2,3,3,3-Tetrafluoropropionamide adheres to stringent quality management protocols. Every batch is analyzed using advanced techniques including HPLC, GC, and NMR to ensure high purity and consistent composition. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality system is designed to meet the rigorous standards required for pharmaceutical and electronic grade intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.