Description

Z-Glu-Gly-Oh is a protected dipeptide building block, specifically the benzyloxycarbonyl (Z) derivative of glutamyl-glycine. This compound is a critical intermediate in solid-phase peptide synthesis (SPPS), valued for its role in constructing complex peptide sequences with precise control over the glutamic acid side chain. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers developing therapeutic peptides, biochemical tools, and novel materials. Its reliable quality and consistent performance are essential for ensuring high yields and purity in advanced synthetic workflows.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental building block for the controlled incorporation of glutamic acid residues into custom peptide sequences.
• Pharmaceutical Research & Development: Used in the synthesis of peptide-based drug candidates, including hormone analogs, enzyme inhibitors, and targeted therapeutics.
• Bioconjugation & Probe Development: Serves as a linker or spacer molecule in the creation of labeled peptides for diagnostic assays and imaging studies.
• Biochemical Research: Employed in studying enzyme-substrate interactions, protein folding, and as a standard in analytical method development.
• Fine Chemical Intermediate: A key precursor for more complex, multi-functional peptide fragments in custom synthesis projects.

Basic Information

Product Name	Z-Glu-Gly-Oh
CAS No.	1634-89-5
Molecular Formula	C₁₅H₁₈N₂O₇
Molecular Weight	338.31 g/mol
Synonyms	N-Benzyloxycarbonyl-L-glutamyl-glycine; Z-L-Glutamyl-glycine; Cbz-Glu-Gly-OH; N-Carbobenzoxy-L-glutamylglycine; Nα-Cbz-L-glutamyl-glycine; (2S)-2-[[2-[(2-Benzyloxycarbonylamino)-4-carboxybutanoyl]amino]acetic acid; L-Glutamic acid, N-(benzyloxycarbonyl)-, glycyl-; Z-Glu-Gly
EINECS	216-658-7

Quality Control

Our Z-Glu-Gly-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and synthesis applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere in a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.