Description

n-Hydroxy-4-Nitrobenzamide is a specialized organic compound featuring both a nitro group and a hydroxamic acid moiety. This unique structure makes it a valuable intermediate and reagent in advanced chemical synthesis, particularly for the development of pharmaceuticals and agrochemicals. It is primarily sought after by research institutions and industrial manufacturers in the life sciences sector for its role in creating novel bioactive molecules and metalloenzyme inhibitors.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting enzymes like histone deacetylases (HDACs).
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its bioactive nitroaromatic structure.
• Chemical Synthesis Reagent: Serves as a versatile precursor for introducing the N-hydroxyamide functional group into more complex molecules.
• Metalloenzyme Inhibitor Studies: Employed in biochemical research as a model compound or precursor for inhibitors of metal-dependent enzymes.
• Material Science Research: Investigated for potential use in creating specialized polymers or ligands for metal-organic frameworks (MOFs).

Basic Information

Product Name	n-Hydroxy-4-Nitrobenzamide
CAS No.	1613-76-9
Molecular Formula	C7H6N2O4
Molecular Weight	182.14 g/mol
Synonyms	4-Nitrobenzohydroxamic Acid; p-Nitrobenzohydroxamic Acid; N-Hydroxy-4-nitrobenzamide; Benzamide, N-hydroxy-4-nitro-; 4-Nitro-N-hydroxybenzamide; HXA; 4-NBAHA; 1613-76-9
EINECS	216-559-7

Quality Control

Our n-Hydroxy-4-Nitrobenzamide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial use. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in a dark place.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	215 - 220 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.