Description

1-Pyrrolidinecarbonyl Fluoride, 2,2-Difluoro- (7Ci,8Ci) is a specialized fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, where the introduction of fluorine atoms is critical for modulating biological activity and metabolic stability. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly in protease inhibitor research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides where fluorine substitution enhances efficacy and environmental profile.
• Material Science Precursor: Serves as a monomer or modifying agent in the creation of specialty polymers and advanced materials with unique surface properties.
• Fluorination Reagent: Acts as a source of the difluoromethyl or carbonyl fluoride moiety in selective fluorination reactions under controlled conditions.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new reaction pathways and creating novel fluorinated compound libraries.
• Ligand and Catalyst Development: Utilized in the synthesis of novel fluorinated ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	1-Pyrrolidinecarbonyl Fluoride, 2,2-Difluoro- (7Ci,8Ci)
CAS No.	1597-47-3
Molecular Formula	C5H7F3NO
Molecular Weight	154.11 g/mol
Synonyms	2,2-Difluoro-1-pyrrolidinecarbonyl fluoride; 2,2-Difluoropyrrolidine-1-carbonyl fluoride; 1-(Fluorocarbonyl)-2,2-difluoropyrrolidine; 2,2-Difluoro-N-fluorocarbonylpyrrolidine; Pyrrolidine, 2,2-difluoro-1-(fluorocarbonyl)-; 1597-47-3 (CAS RN)
EINECS	Contact for details

Quality Control

Our 1-Pyrrolidinecarbonyl Fluoride, 2,2-Difluoro- (7Ci,8Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high purity and consistency suitable for research and process development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.