Description

2-Fluoroglutaric Acid is a fluorinated derivative of glutaric acid, serving as a versatile and valuable building block in advanced organic synthesis. Its unique structure, featuring a fluorine atom on the carbon backbone, makes it a critical intermediate for introducing fluorinated motifs into target molecules, which can significantly alter their physicochemical and biological properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of fluorinated drug candidates, potentially enhancing metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in creating novel fluorinated pesticides and herbicides, where the fluorine atom can improve efficacy and environmental profile.
• Biochemical Research: Acts as a substrate or inhibitor in enzymatic studies, particularly those involving fluorinated analogs of natural metabolites.
• Material Science: Employed in the synthesis of specialty polymers and advanced materials where fluorination imparts desired properties like chemical resistance or altered surface energy.
• Organic Synthesis Building Block: Utilized in various name reactions and coupling chemistries to construct complex, fluorinated organic molecules for diverse applications.

Basic Information

Product Name	2-Fluoroglutaric Acid
CAS No.	1578-67-2
Molecular Formula	C5H7FO4
Molecular Weight	150.11 g/mol
Synonyms	2-Fluoropentanedioic Acid; Fluoroglutaric Acid; DL-2-Fluoroglutaric Acid; (±)-2-Fluoroglutaric Acid; 2-Fluoro-1,5-pentanedioic Acid; α-Fluoroglutaric Acid; NSC 528124
EINECS	Contact for details

Quality Control

Our 2-Fluoroglutaric Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and titration methods, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can provide material for regulatory filings upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.