Description

N,n-Dimethyltrifluoroacetamide is a high-purity, versatile fluorinated amide solvent and reagent. This compound is valued for its unique combination of strong solvating power, high thermal stability, and low nucleophilicity, making it an excellent medium for demanding chemical processes. It is primarily sought by the pharmaceutical, agrochemical, and specialty chemical industries for applications ranging from peptide synthesis and polymer chemistry to serving as a non-aqueous electrolyte component.

Application

• Pharmaceutical Intermediate Synthesis: Acts as a key solvent and reagent in the synthesis of complex drug molecules, particularly where fluorinated moieties are required.
• Peptide Coupling Reagent: Used as an activating agent or solvent in peptide bond formation, offering advantages in yield and purity.
• Polymer & Resin Chemistry: Serves as a reaction medium for polymerization processes and the production of high-performance fluorinated polymers.
• Electrolyte Solvent: Employed in advanced battery systems and electrochemical applications due to its high dielectric constant and stability.
• Agrochemical Formulation: Utilized as a co-solvent or intermediate in the synthesis of modern, effective pesticides and herbicides.
• Laboratory Research & Development: A valuable solvent for NMR spectroscopy and other analytical techniques, as well as for exploratory organic synthesis.

Basic Information

Product Name	N,n-Dimethyltrifluoroacetamide
CAS No.	1547-87-1
Molecular Formula	C4H6F3NO
Molecular Weight	141.09 g/mol
Synonyms	N,N-Dimethyl-2,2,2-trifluoroacetamide; Trifluoro-N,N-dimethylacetamide; 2,2,2-Trifluoro-N,N-dimethylacetamide; Dimethyltrifluoroacetamide; TFDMA; DMTA; Acetamide, 2,2,2-trifluoro-N,N-dimethyl-
EINECS	Contact for details

Quality Control

Our N,n-Dimethyltrifluoroacetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure it meets the high-purity standards required for pharmaceutical and advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and fluorides. The container must be kept tightly sealed due to its hygroscopic nature.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.380 - 1.390
Density (20°C)	1.25 - 1.35 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.