Description

L-p-Hydroxyamphetamine is a chiral organic compound belonging to the class of substituted amphetamines. This high-purity intermediate is critical for pharmaceutical research and development, particularly in the synthesis of specialized active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel central nervous system (CNS) agents and other specialized APIs.
• Biochemical Research: Used as a reference standard or precursor in neuropharmacology and metabolic pathway studies.
• Analytical Chemistry: Serves as a high-purity standard for method development and validation in chromatographic analysis (HPLC, GC).
• Asymmetric Synthesis: Employed as a chiral synthon or resolving agent in the production of enantiomerically pure compounds.
• Metabolite Studies: Used in the research and synthesis of drug metabolites for pharmacokinetic and toxicological profiling.

Basic Information

Item	Details
Product Name	L-p-Hydroxyamphetamine
CAS No.	1518-89-4
Molecular Formula	C9H13NO
Molecular Weight	151.21 g/mol
Synonyms	(-)-p-Hydroxyamphetamine; L-(-)-p-Hydroxyamphetamine; (R)-(-)-4-Hydroxyamphetamine; (R)-4-(2-Aminopropyl)phenol; L-PHA; p-Hydroxy-(R)-amphetamine; 1-(4-Hydroxyphenyl)-2-aminopropane (R)-form; Levo-p-hydroxyamphetamine
EINECS	Contact for details

Quality Control

Our L-p-Hydroxyamphetamine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.