Description

Ethyl 4,4,4-Trifluoro-3-(Trifluoromethyl)Crotonate is a high-value fluorinated building block characterized by its reactive α,β-unsaturated ester functionality flanked by two perfluoroalkyl groups. This compound is essential for introducing the highly lipophilic and electron-withdrawing trifluoromethyl group into complex molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for synthesizing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of fluorinated analogs of bioactive molecules, enhancing their metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the CF3 group improves efficacy and environmental profile.
• Material Science Precursor: Serves as a monomer or cross-linking agent for creating specialty fluoropolymers with unique surface properties and chemical resistance.
• Organic Synthesis Building Block: Employed in Michael additions, cycloadditions, and other C-C bond-forming reactions to construct complex, fluorinated organic compounds.
• Liquid Crystal & OLED Research: Utilized in the synthesis of fluorinated components for electronic display materials to modify dielectric constants and alignment properties.

Basic Information

Product Name	Ethyl 4,4,4-Trifluoro-3-(Trifluoromethyl)Crotonate
CAS No.	1513-60-6
Molecular Formula	C7H5F6O2
Molecular Weight	226.11 g/mol
Synonyms	Ethyl 4,4,4-Trifluoro-3-(trifluoromethyl)-2-butenoate; 2-Butenoic acid, 4,4,4-trifluoro-3-(trifluoromethyl)-, ethyl ester; Ethyl (E)-4,4,4-Trifluoro-3-(trifluoromethyl)crotonate; Ethyl Perfluorocrotonate; 3-(Trifluoromethyl)-4,4,4-trifluorocrotonic Acid Ethyl Ester; ETFC; TFMC Ethyl Ester
EINECS	Contact for details

Quality Control

Every batch of Ethyl 4,4,4-Trifluoro-3-(Trifluoromethyl)Crotonate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the precise requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.