Description

N,N'-Bis(Trifluoroacetyl)-L-Cystine Dimethyl Ester is a high-purity, protected derivative of the amino acid L-cystine, specifically engineered for advanced synthetic applications. This compound is critical for researchers and manufacturers requiring precise control over peptide synthesis and chemical modifications. It is primarily utilized in the pharmaceutical, biotechnology, and fine chemical industries for developing novel therapeutic agents, biochemical probes, and complex organic molecules.

Application

• Peptide Synthesis Intermediate: Serves as a key building block in solid-phase and solution-phase peptide synthesis, where the trifluoroacetyl (TFA) groups act as protective groups for the amino functionalities.
• Pharmaceutical Research & Development: Used in the R&D of cysteine-containing peptides and proteins, including potential drug candidates targeting various diseases.
• Bioconjugation Chemistry: Facilitates the site-specific modification of biomolecules for creating antibody-drug conjugates (ADCs) or diagnostic probes.
• Chemical Biology Studies: Employed in the synthesis of labeled or modified cystine derivatives for studying protein structure, function, and interactions.
• Fine Chemical Synthesis: Acts as a chiral synthon for the asymmetric synthesis of complex organic compounds and natural product analogs.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	N,N'-Bis(Trifluoroacetyl)-L-Cystine Dimethyl Ester
CAS No.	1492-83-7
Molecular Formula	C12H12F6N2O6S2
Molecular Weight	458.36 g/mol
Synonyms	L-Cystine, N,N'-bis(trifluoroacetyl)-, dimethyl ester; Bis(trifluoroacetyl)cystine dimethyl ester; Dimethyl N,N'-bis(trifluoroacetyl)-L-cystinate; N,N'-Di(trifluoroacetyl)-L-cystine dimethyl ester; (2R,2'R)-3,3'-Disulfanediylbis(2-((2,2,2-trifluoroacetyl)amino)propanoic acid) dimethyl ester; TFA-L-Cystine(OMe)2; Protected L-Cystine Dimethyl Ester
EINECS	Contact for details

Quality Control

Our N,N'-Bis(Trifluoroacetyl)-L-Cystine Dimethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing purity, physical properties, and spectroscopic data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.