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Z-Ser(Tos)-Ome CAS NO 1492-52-0
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CAS No.:1492-52-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Z-Ser(Tos)-Ome is a protected serine derivative, specifically the O-tosyl (Tos) protected form of serine methyl ester. This compound serves as a crucial building block in organic synthesis, particularly in the production of complex peptides and pharmaceuticals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for drug discovery and development processes.
Application
- Peptide Synthesis: As a key protected amino acid derivative for the solid-phase and solution-phase synthesis of custom peptides.
- Pharmaceutical Intermediates: Used in the research and production of active pharmaceutical ingredients (APIs) and drug candidates.
- Bioconjugation: Acts as a reagent for modifying proteins or other biomolecules, leveraging the reactive tosyl group.
- Chemical Biology Research: Employed in the study of enzyme mechanisms and protein-protein interactions.
- Protecting Group Chemistry: Serves as a model compound in methodologies for the selective protection and deprotection of amino acid side chains.
- Libraries for Screening: Used to generate combinatorial libraries for high-throughput screening in drug discovery.
Basic Information
| Product Name | Z-Ser(Tos)-Ome |
| CAS No. | 1492-52-0 |
| Molecular Formula | C19H21NO7S |
| Molecular Weight | 407.44 g/mol |
| Synonyms | N-Carbobenzoxy-O-tosyl-L-serine methyl ester; Z-Ser(Tos)-OMe; Cbz-Ser(Tos)-OMe; Benzyloxycarbonyl-O-(p-toluenesulfonyl)-L-serine methyl ester; (2S)-2-{[(Benzyloxy)carbonyl]amino}-3-[(4-methylphenyl)sulfonyl]oxypropanoic acid methyl ester; Nα-Cbz-O-tosyl-L-serine methyl ester; L-Serine, N-[(phenylmethoxy)carbonyl]-O-[(4-methylphenyl)sulfonyl]-, methyl ester |
| EINECS | Contact for details |
Quality Control
Our Z-Ser(Tos)-Ome is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and GMP-guided applications. Comprehensive Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference standard |
| Assay (HPLC) | ≥98.0% |
| Optical Rotation | Contact for details |
| Loss on Drying | ≤0.5% |
| Heavy Metals | ≤20 ppm |
| Residual Solvents | Complies with ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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