Description

Di-n-Tfa-L-Lysine Methyl Ester is a protected derivative of the essential amino acid L-Lysine, featuring trifluoroacetyl (Tfa) protecting groups on the side-chain amine and a methyl ester on the carboxyl group. This compound is a crucial high-purity building block in advanced organic synthesis, particularly in peptide chemistry and pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for the controlled synthesis of complex peptides and novel bioactive molecules.

Application

• Peptide Synthesis: A key protected intermediate for the solid-phase and solution-phase synthesis of lysine-containing peptides.
• Pharmaceutical Research: Used in the development and scale-up of active pharmaceutical ingredients (APIs) and peptide-based therapeutics.
• Bioconjugation: Serves as a precursor for creating labeled peptides or peptide-drug conjugates for diagnostic and therapeutic applications.
• Fine Chemical Production: Employed in the manufacture of specialized amino acid derivatives and custom organic compounds.
• Biochemical Research: Utilized as a standard or reagent in studies involving protein structure, function, and enzyme-substrate interactions.

Basic Information

Product Name	Di-n-Tfa-L-Lysine Methyl Ester
CAS No.	1478-74-6
Molecular Formula	C11H15F6N2O5
Molecular Weight	354.24 g/mol
Synonyms	L-Lysine, N2,N6-bis(trifluoroacetyl)-, methyl ester; Methyl N2,N6-bis(trifluoroacetyl)-L-lysinate; Nα,Nε-Bis(trifluoroacetyl)-L-lysine methyl ester; BIS(TRIFLUOROACETYL)-L-LYSINE METHYL ESTER; Di-N-trifluoroacetyl-L-lysine methyl ester; (S)-Methyl 2,6-bis(2,2,2-trifluoroacetamido)hexanoate; Lys(Tfa)2-OMe; L-Lysine, N6,N2-bis(trifluoroacetyl)-, methyl ester
EINECS	Contact for details

Quality Control

Our Di-n-Tfa-L-Lysine Methyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and optical rotation measurement, to ensure high chemical purity and chiral integrity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee batch-to-batch consistency and support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.