Description

N,n-Dimethylformamide-15N is a stable isotope-labeled analog of the essential polar aprotic solvent, dimethylformamide (DMF), where the nitrogen atom is enriched with the 15N isotope. This compound is critical for advanced analytical and research applications where isotopic tracing is required, providing a non-radioactive, precise tool for mechanistic studies and quantitative analysis. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and analytical service providers engaged in NMR spectroscopy, mass spectrometry, and metabolic pathway research.

Application

• NMR Spectroscopy Internal Standard: Used as a chemical shift reference and quantitative standard in nuclear magnetic resonance (NMR) studies, particularly for 15N-NMR.
• Mass Spectrometry Tracer: Serves as a stable isotope-labeled internal standard in LC-MS and GC-MS for the accurate quantification of DMF or related compounds in complex matrices.
• Metabolic Pathway Analysis: Employed in pharmaceutical and biochemical research to trace the fate of the DMF moiety or related metabolites using isotope ratio monitoring.
• Chemical Reaction Mechanism Studies: Utilized to elucidate reaction pathways and kinetics in organic synthesis and catalysis where DMF acts as a solvent or reagent.
• Production of Labeled Compounds: Acts as a labeled building block for the synthesis of more complex 15N-enriched molecules for research purposes.

Basic Information

Product Name	N,n-Dimethylformamide-15N
CAS No.	1449-84-9
Molecular Formula	C3H715NO
Molecular Weight	74.10 g/mol (for 15N labeled form)
Synonyms	DMF-15N; [15N]Dimethylformamide; N,N-Dimethyl[15N]formamide; (15N)Dimethylformamide; N,N-Dimethylformamide (nitrogen-15); Formdimethylamide-15N; 1449-84-9; NSC 5356
EINECS	Contact for details

Quality Control

Our N,n-Dimethylformamide-15N is produced under controlled conditions to ensure high isotopic and chemical purity, meeting the stringent requirements of research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (Atom % 15N), chemical purity, and identity confirmation. We adhere to rigorous internal quality standards to ensure batch-to-batch consistency and reliability for your critical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR)	Conforms to structure
Isotopic Enrichment (Atom % 15N)	≥ 98%
Assay (GC)	≥ 99.0%
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.