Description

Ans-Na CAS NO 1445-19-8 is the sodium salt form of 8-anilino-1-naphthalenesulfonic acid (ANS), a widely used fluorescent probe and hydrophobic dye. This compound is valued for its significant fluorescence enhancement upon binding to hydrophobic sites in proteins and membranes, making it a critical tool for studying conformational changes. It is primarily needed by researchers and manufacturers in the biochemistry, biophysics, and pharmaceutical development sectors for applications ranging from protein folding studies to drug discovery assays.

Application

• Protein Binding & Conformational Studies: As a fluorescent probe to monitor protein unfolding, aggregation, and ligand binding by detecting exposed hydrophobic regions.
• Membrane & Liposome Research: Used to investigate membrane fluidity, integrity, and the interaction of peptides or drugs with lipid bilayers.
• Drug Discovery Screening: Employed in high-throughput assays to identify compounds that inhibit or promote protein-protein interactions or misfolding.
• Biomolecular Assay Development: Serves as a key component in developing fluorescence-based diagnostic and research kits.
• Surfactant & Micelle Characterization: Utilized to study critical micelle concentration (CMC) and the properties of amphiphilic molecules.
• Academic & Industrial R&D: A fundamental research chemical in universities and corporate labs for fundamental life science research.

Basic Information

Product Name	Ans-Na CAS NO 1445-19-8
CAS No.	1445-19-8
Molecular Formula	C16H12NNaO3S
Molecular Weight	321.32 g/mol
Synonyms	8-Anilino-1-naphthalenesulfonic acid sodium salt; 1-Anilino-8-naphthalenesulfonate sodium salt; ANS sodium salt; Ammonium 8-anilino-1-naphthalenesulfonate; Bis-ANS; 1,8-ANS Na salt; Fluorescent probe ANS; Hydrophobic dye ANS
EINECS	215-898-1

Quality Control

Our Ans-Na is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistent performance as a fluorescent probe. Certificates of Analysis (COA) detailing purity, identity, and fluorescence properties are available upon request to support your research and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to greenish-yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Fluorescence Properties	Conforms to reference standard
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.