Description

Ribosome-Inactivating Protein, Aspergillus is a potent enzymatic toxin derived from the *Aspergillus* genus of fungi. This protein functions by catalytically inactivating ribosomes, halting protein synthesis and leading to cell death, which makes it a critical tool for targeted biological research and therapeutic development. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical developers focused on oncology, virology, and immunology. The product is supplied to the global market with a focus on high purity and batch-to-batch consistency for reliable experimental and pre-clinical outcomes.

Application

• Biomedical Research: Used as a key reagent in studying protein synthesis inhibition, ribosome structure, and mechanisms of cytotoxicity.
• Immunotoxin Development: Serves as the toxic payload in the construction of antibody-drug conjugates (ADCs) and other targeted cancer therapies.
• Antiviral Studies: Investigated for its potential to inhibit viral replication by targeting host or viral protein production mechanisms.
• Cell Biology & Apoptosis Research: Employed to induce controlled cell death in various cell lines to study apoptotic pathways.
• Plant Pathology & Mycology: Used in research on fungal pathogenesis and the role of fungal toxins in plant disease.
• Biodefense & Toxinology: Studied as a model toxin for understanding biological threats and developing countermeasures.

Basic Information

Product Name	Ribosome-Inactivating Protein, Aspergillus
CAS No.	1407-48-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Aspergillus Ribosome-Inactivating Protein; RIP, Aspergillus; Aspergillus Toxin; N-Glycosidase, Aspergillus; 28S rRNA N-glycosidase; Protein Synthesis Inhibitor from Aspergillus; Antiviral Protein, Aspergillus; Fungal Ribotoxin
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized for biological activity, purity, and identity using advanced analytical techniques. Certificates of Analysis (COA) detailing specific results for activity (e.g., IC50 in a cell-free translation assay), purity by SDS-PAGE and HPLC, and endotoxin levels are available upon request. We adhere to a quality management system suitable for research and pre-clinical grade biologics.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted solutions should be aliquoted and stored at -70°C or lower to prevent loss of activity. Avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (SDS-PAGE)	Single major band corresponding to expected molecular weight
Purity (HPLC)	≥ 90%
Biological Activity (IC50)	Specified per batch on COA
Endotoxin Level	< 1.0 EU/µg
Protein Content (UV)	≥ 80%
Solubility	Soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.