Description

α-(1-Methylpropyl)-α-(2-Morpholinoethyl)-1-Naphthaleneacetonitrile is a specialized organic compound featuring a naphthalene backbone substituted with morpholino and methylpropyl groups. This unique structure makes it a valuable intermediate in advanced organic synthesis, particularly for the development of complex pharmaceutical molecules and fine chemicals. It is primarily sought by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries. The compound's specific stereochemistry and functional groups are critical for constructing target molecules with desired biological or chemical activity.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), potentially for central nervous system (CNS) or cardiovascular drugs.
• Agrochemical Research: Used in the development of novel pesticides, herbicides, or plant growth regulators requiring complex nitrile and amine functionalities.
• Fine Chemical Synthesis: Serves as a precursor for dyes, pigments, and other high-value specialty chemicals where the naphthalene structure is essential.
• Academic & Industrial R&D: Employed in methodological studies and as a model compound for developing new synthetic routes involving chiral centers and protected amines.
• Ligand and Catalyst Development: Potential use in creating chiral ligands or organocatalysts due to the presence of the morpholino group, which can act as a coordinating site.

Basic Information

Product Name	α-(1-Methylpropyl)-α-(2-Morpholinoethyl)-1-Naphthaleneacetonitrile
CAS No.	1241-65-2
Molecular Formula	C22H30N2O
Molecular Weight	338.49 g/mol
Synonyms	1-Naphthaleneacetonitrile, α-(1-methylpropyl)-α-[2-(4-morpholinyl)ethyl]-; α-(1-Methylpropyl)-α-(2-morpholinoethyl)-1-naphthaleneacetonitrile; α-sec-Butyl-α-(2-morpholinoethyl)-1-naphthaleneacetonitrile; 2-(4-Morpholinyl)-α-(1-methylpropyl)-1-naphthaleneacetonitrile; (RS)-α-(1-Methylpropyl)-α-(2-morpholinoethyl)-1-naphthaleneacetonitrile; (±)-α-(1-Methylpropyl)-α-(2-morpholinoethyl)-1-naphthaleneacetonitrile
EINECS	Contact for details

Quality Control

Our α-(1-Methylpropyl)-α-(2-Morpholinoethyl)-1-Naphthaleneacetonitrile is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and structural confirmation. A Certificate of Analysis (COA) detailing specific results for identity, purity, and impurities is provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates, and specifications can be aligned with customer-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.