Description

Levomepromazine Hydrochloride is a high-purity pharmaceutical active ingredient belonging to the phenothiazine class of compounds. This compound is critical for the formulation of specific antipsychotic and sedative medications, offering reliable therapeutic effects. It is primarily required by pharmaceutical manufacturers, research institutions, and fine chemical suppliers engaged in the development and production of neuropsychiatric drugs. Consistent quality and supply chain integrity are paramount for this advanced intermediate.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the formulation of antipsychotic and sedative injectable and oral medications.
• Reference Standard: Serves as a certified standard in analytical laboratories for quality control and method validation.
• Biochemical Research: Used in neuroscience and pharmacological studies to investigate neurotransmitter receptor interactions and mechanisms of action.
• Veterinary Medicine: Applied in veterinary practice for sedation and management of agitation in animals.
• Precursor Synthesis: Acts as a key intermediate in the synthesis of more complex phenothiazine derivatives for research purposes.

Basic Information

Product Name	Levomepromazine Hydrochloride
CAS No.	1236-99-3
Molecular Formula	C19H24N2OS•HCl
Molecular Weight	364.93 g/mol
Synonyms	Methotrimeprazine Hydrochloride; Levoprome; Nozinan; 2-Methoxy-10-(2-methyl-3-dimethylaminopropyl)phenothiazine Hydrochloride; (-)-Methotrimeprazine Hydrochloride; (2R)-3-(2-Methoxyphenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine Hydrochloride
EINECS	214-983-6

Quality Control

Our Levomepromazine Hydrochloride is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical applications, with typical purity levels exceeding 99.0%. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results for identity, assay, related substances, residual solvents, and other pharmacopeial parameters. We can support compliance with various regulatory frameworks, including cGMP, upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 99.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.