Description

Cbz-(S)-3-Amino-2-Phenylpropanoic Acid CAS NO 1233-79-0 is a protected amino acid derivative, specifically the carboxybenzyl (Cbz) derivative of (S)-3-amino-2-phenylpropanoic acid. This compound is a crucial chiral building block in the synthesis of complex peptides and peptidomimetics, offering a versatile handle for solid-phase and solution-phase peptide chemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), diagnostic agents, and novel therapeutic peptides.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Serves as a protected amino acid building block in both solid-phase peptide synthesis (SPPS) and solution-phase methodologies.
• Bioconjugation & Probe Development: Used in the creation of labeled peptides for diagnostic assays, imaging probes, and biochemical research tools.
• Chemical Biology Research: Employed in the study of enzyme-substrate interactions, receptor binding, and the structure-activity relationships (SAR) of peptides.
• Catalyst & Ligand Synthesis: Acts as a precursor for chiral ligands and catalysts used in asymmetric synthesis.
• Academic & R&D Laboratories: A standard reagent for graduate-level research and discovery chemistry focused on amino acid chemistry and peptide science.

Basic Information

Product Name	Cbz-(S)-3-Amino-2-Phenylpropanoic Acid
CAS No.	1233-79-0
Molecular Formula	C17H17NO4
Molecular Weight	299.32 g/mol
Synonyms	N-Carboxybenzyl-(S)-3-amino-2-phenylpropanoic acid; N-[(Benzyloxy)carbonyl]-3-amino-2-phenylpropanoic acid; (S)-2-(Benzyloxycarbonylamino)-3-phenylpropanoic acid; Z-3-Amino-2-phenylpropionic acid; Z-(S)-A3Ppa-OH; N-Cbz-3-amino-2-phenylpropionic acid; (S)-3-((Benzyloxycarbonyl)amino)-2-phenylpropanoic acid; Nα-Cbz-(S)-3-amino-2-phenylpropionic acid
EINECS	Contact for details

Quality Control

Our Cbz-(S)-3-Amino-2-Phenylpropanoic Acid is manufactured under strict quality control protocols. Each batch is tested to ensure high chemical purity and chiral integrity, meeting the stringent requirements for pharmaceutical R&D and fine chemical synthesis. Certificates of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.