Description

(7R)-1,3,4,7,7Aα,8,9,10,11,13,14,14Aα-Dodecahydro-7α,14α-Methano-2H,6H-Dipyrido[1,2-A:1',2'-E][1,5]Diazocin-6-One CAS NO 1218-51-5 is a complex, stereochemically defined heterocyclic compound with a bridged diazocine structure. This compound is of significant interest as a key synthetic intermediate and a valuable scaffold in advanced organic and medicinal chemistry research. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams for developing novel active pharmaceutical ingredients (APIs) and exploring new chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of complex drug candidates, particularly those targeting neurological and cardiovascular pathways.
• Medicinal Chemistry Research: Used as a privileged scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Organic Synthesis Reagent: Employed in advanced organic transformations, including asymmetric synthesis and the construction of complex polycyclic frameworks.
• Chemical Biology Probe: Acts as a core structure for developing molecular probes to study enzyme function and receptor-ligand interactions.
• Academic & Institutional Research: Utilized in universities and research institutes for fundamental studies in heterocyclic chemistry and synthetic methodology.

Basic Information

Product Name	(7R)-1,3,4,7,7Aα,8,9,10,11,13,14,14Aα-Dodecahydro-7α,14α-Methano-2H,6H-Dipyrido[1,2-A:1',2'-E][1,5]Diazocin-6-One
CAS No.	1218-51-5
Molecular Formula	C₁₄H₂₀N₂O
Molecular Weight	232.32 g/mol
Synonyms	(7R)-7,14-Methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-6-one, dodecahydro-; 7,14-Methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-6-one, dodecahydro-, (7R)-; Bridged Diazocine Derivative; (7R)-Dodecahydro-7α,14α-methanodipyrido[1,2-a:1',2'-e][1,5]diazocin-6-one; 1218-51-5; (7R)-enantiomer of the diazocine lactam
EINECS	Contact for details

Quality Control

Our (7R)-1,3,4,7,7Aα,8,9,10,11,13,14,14Aα-Dodecahydro-7α,14α-Methano-2H,6H-Dipyrido[1,2-A:1',2'-E][1,5]Diazocin-6-One is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing purity (typically by HPLC), chiral purity, and related substances are provided and available upon request. We support custom synthesis to meet specific purity or packaging requirements for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.