Description

Oxidopamine CAS NO 1199-18-4 is a selective neurotoxin and research chemical widely used in neuroscience and pharmacological studies. This compound is particularly valued for its ability to selectively destroy catecholaminergic neurons, making it a critical tool for modeling neurodegenerative diseases like Parkinson's. Researchers in pharmaceutical R&D, academic institutions, and biotechnology rely on high-purity oxidopamine to ensure the reproducibility and validity of their experimental models.

Application

• Neurodegenerative Disease Research: Primary tool for creating experimental models of Parkinson's disease by inducing selective dopaminergic neuron degeneration.
• Pharmacological Screening: Used in high-throughput assays to evaluate the neuroprotective effects of potential drug candidates.
• Neuroscience Studies: Fundamental research on catecholamine pathways, neuronal apoptosis, and mechanisms of selective neuronal vulnerability.
• Toxicology Investigations: Studying the mechanisms and effects of neurotoxins on the central and peripheral nervous systems.
• Cell Culture & In Vitro Models: Application in cell-based assays to study neurotoxicity and cell death mechanisms in controlled environments.
• Preclinical Animal Studies: Administration in rodent models to study behavioral, biochemical, and histological correlates of neurodegeneration.

Basic Information

Product Name	Oxidopamine
CAS No.	1199-18-4
Molecular Formula	C8H11NO3
Molecular Weight	169.18 g/mol
Synonyms	6-Hydroxydopamine; 6-Hydroxydopamine HBr; 6-OHDA; 2,4,5-Trihydroxyphenethylamine; 6-Hydroxy dopamine; Oxidopamine hydrobromide; NSC 36915
EINECS	214-842-8

Quality Control

Our Oxidopamine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, essential for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant standards for research chemicals, and our quality management system supports traceability and regulatory compliance for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Due to its sensitivity, the product should be stored under an inert atmosphere to prevent oxidation. Keep the container tightly sealed to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.