Description

Raptinal CAS NO 1176-09-6 is a potent and selective small molecule compound of significant interest in biochemical and pharmaceutical research. Its primary value lies in its well-characterized mechanism of action as a direct activator of apoptosis, making it a critical tool for studying programmed cell death pathways. This compound is essential for researchers and developers in academic institutions, biotechnology firms, and pharmaceutical companies focused on oncology, neurobiology, and drug discovery.

Application

• Biochemical Research: Used as a potent and rapid inducer of apoptosis (programmed cell death) in various cell culture models to study cell death mechanisms.
• Cancer Research: Employed in vitro to investigate tumor cell sensitivity, screen for anti-cancer compounds, and explore resistance mechanisms.
• Neurodegenerative Disease Studies: Applied in research models to understand neuronal cell death associated with conditions like Alzheimer's and Parkinson's disease.
• Drug Discovery & Development: Serves as a reference compound and a pharmacological tool for validating assays and exploring novel therapeutic targets related to apoptosis.
• Signal Pathway Analysis: Utilized to dissect and understand the BAX-mediated mitochondrial apoptosis pathway in molecular biology.
• High-Throughput Screening (HTS): Acts as a control compound in cell-based assays to identify new modulators of apoptosis.

Basic Information

Product Name	Raptinal
CAS No.	1176-09-6
Molecular Formula	C17H14N4O4S
Molecular Weight	370.38 g/mol
Synonyms	Raptinal; BAX Activator; Apoptosis Activator 2; N-[(4-Methoxyphenyl)sulfonyl]-3-nitro-1H-indole-2-carboxamide; 3-Nitro-N-(4-methoxybenzenesulfonyl)-1H-indole-2-carboxamide; NSC 83265; CAS 1176-09-6
EINECS	Contact for details

Quality Control

We supply Raptinal in high-purity grades suitable for research applications. Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your research integrity and documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.