Description

Z-Tyr-Oh CAS NO 1164-16-5 is a protected tyrosine derivative, specifically the benzyloxycarbonyl (Z or Cbz) protected form of L-tyrosine. This compound serves as a crucial chiral building block and intermediate in sophisticated organic synthesis, particularly in peptide chemistry and pharmaceutical research. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-purity, protected amino acids for the development of novel therapeutic peptides and complex organic molecules.

Application

• Peptide Synthesis: A fundamental building block for the solid-phase and solution-phase synthesis of peptides, where the Z-group provides orthogonal protection for the amine functionality.
• Pharmaceutical Intermediates: Serves as a key chiral intermediate in the research and production of active pharmaceutical ingredients (APIs), especially those containing tyrosine residues.
• Bioconjugation & Probe Development: Used in the preparation of modified peptides and proteins for biochemical research, diagnostic assays, and targeted drug delivery systems.
• Chemical Biology Research: Employed in the synthesis of peptide-based inhibitors, substrates, and molecular probes to study enzyme function and biological pathways.
• Fine Chemical Synthesis: Acts as a versatile starting material for the synthesis of more complex, non-peptidic organic molecules requiring a chiral phenolic scaffold.

Basic Information

Product Name	Z-Tyr-Oh CAS NO 1164-16-5
CAS No.	1164-16-5
Molecular Formula	C17H17NO5
Molecular Weight	315.32 g/mol
Synonyms	N-Carbobenzyloxy-L-tyrosine; N-Cbz-L-tyrosine; (S)-2-(((Benzyloxy)carbonyl)amino)-3-(4-hydroxyphenyl)propanoic acid; Z-L-Tyrosine; Cbz-L-Tyrosine; Z-Tyrosine-OH; CBZ-TYR-OH; N-α-Carbobenzoxy-L-tyrosine
EINECS	214-571-3

Quality Control

Our Z-Tyr-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with your research and cGMP-grade production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation [α]	-15.0° to -18.0° (c=1 in AcOH)
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.