Description

Z-Tyr-Ohhydrate is a protected tyrosine derivative, specifically the benzyloxycarbonyl (Z or Cbz) protected form of tyrosine hydrate. This compound is a crucial building block in peptide synthesis, offering a strategic combination of an N-terminal protecting group and a free carboxylic acid for controlled chain elongation. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel peptides and peptidomimetics. The high-purity grade ensures reliable and reproducible results in sensitive synthetic applications.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled, stepwise assembly of peptide chains.
• Solution-Phase Peptide Synthesis: Used in classical coupling strategies for constructing specific peptide sequences.
• Pharmaceutical Research: Serves as a critical raw material in the R&D of therapeutic peptides targeting various diseases.
• Bioconjugation: The free carboxyl group allows for conjugation to other molecules, carriers, or surfaces.
• Biochemical Tool Development: Used to create enzyme substrates, inhibitors, or probes for studying biological mechanisms.
• Custom Peptide Production: An essential reagent for CROs and CDMOs producing bespoke peptides for clients.

Basic Information

Product Name	Z-Tyr-Ohhydrate
CAS No.	1164-16-4
Molecular Formula	C17H17NO5 • xH2O
Molecular Weight	307.32 (Anhydrous basis)
Synonyms	N-Carbobenzyloxy-L-tyrosine Hydrate; N-Cbz-L-tyrosine Hydrate; Z-L-Tyrosine Hydrate; (S)-2-(((Benzyloxy)carbonyl)amino)-3-(4-hydroxyphenyl)propanoic Acid Hydrate; Cbz-Tyr-OH Hydrate; N-α-Carbobenzoxy-L-tyrosine Hydrate; Benzyl N-[(1S)-1-Carboxy-2-(4-hydroxyphenyl)ethyl]carbamate Hydrate
EINECS	Contact for details

Quality Control

Our Z-Tyr-Ohhydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation. We provide full traceability and a Certificate of Analysis (COA) with every shipment, detailing all critical quality attributes to ensure it meets the stringent requirements for pharmaceutical research and peptide synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0% (on anhydrous basis)
Optical Rotation [α]D20	-10.0° to -12.0° (c=1 in DMF)
Water Content (KF)	4.0% - 8.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.