Description

H-D-Lys(Z)-Ome . HCl is a protected amino acid derivative, specifically the hydrochloride salt of Nε-benzyloxycarbonyl-D-lysine methyl ester. This compound serves as a crucial chiral building block in the synthesis of complex peptides and peptidomimetics, offering precise stereochemical control. It is primarily utilized by research institutions and pharmaceutical companies engaged in advanced peptide chemistry, medicinal chemistry, and the development of novel therapeutic agents.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a protected D-lysine derivative for the controlled incorporation of D-amino acids into peptide chains.
• Medicinal Chemistry & Drug Discovery: A key intermediate in the research and development of peptide-based pharmaceuticals and bioactive compounds.
• Bioconjugation & Linker Chemistry: Utilized for introducing functional handles or cross-linking agents via its protected amine side chain.
• Synthesis of Peptidomimetics: Enables the creation of metabolically stable analogs of natural peptides for enhanced therapeutic properties.
• Biochemical Research: Used in studies exploring enzyme-substrate interactions, receptor binding, and structure-activity relationships (SAR).
• Production of Custom Peptides: A high-purity starting material for contract research organizations (CROs) and CDMOs manufacturing specialized peptide sequences.

Basic Information

Product Name	H-D-Lys(Z)-Ome . HCl
CAS No.	1158-35-6
Molecular Formula	C15H23ClN2O4
Molecular Weight	330.81 g/mol
Synonyms	Nε-Cbz-D-lysine methyl ester hydrochloride; Methyl Nε-benzyloxycarbonyl-D-lysinate hydrochloride; D-Lysine, N6-(benzyloxycarbonyl)-, methyl ester, hydrochloride; (R)-Methyl 2-amino-6-((benzyloxy)carbonylamino)hexanoate hydrochloride; Z-D-Lys-OMe . HCl; Cbz-D-Lys-OMe . HCl; D-Lys(Z)-OMe . HCl; Benzyloxycarbonyl-D-lysine methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our H-D-Lys(Z)-Ome . HCl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and NMR/IR for structural confirmation. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation [α]D20	+10.0° to +12.0° (c=1 in methanol)
Chiral Purity (HPLC)	≥99.0% D-isomer
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.