Description

n-Carbobenzyloxy-L-Aspartic Acid is a protected derivative of the amino acid L-aspartic acid, widely used as a crucial building block in peptide synthesis. Its primary value lies in providing a versatile and reactive intermediate for the controlled construction of complex peptide chains, particularly in pharmaceutical research and development. This compound is essential for scientists and manufacturers in the fields of pharmaceuticals, biotechnology, and advanced organic chemistry who require high-purity, reliable intermediates for API development and novel peptide-based therapeutics.

Application

• Peptide Synthesis Intermediate: A key protected amino acid for solid-phase and solution-phase peptide synthesis (SPPS).
• Pharmaceutical Research: Building block for the development of peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Bioconjugation: Used in the preparation of peptide-protein conjugates for diagnostic and therapeutic applications.
• Chemical Biology Probes: Synthesis of labeled or modified peptides used as tools for studying biological processes.
• Catalyst and Ligand Preparation: Intermediate in the synthesis of chiral catalysts or complex organic ligands.

Basic Information

Product Name	n-Carbobenzyloxy-L-Aspartic Acid
CAS No.	1152-61-0
Molecular Formula	C12H13NO6
Molecular Weight	267.24 g/mol
Synonyms	N-Cbz-L-Aspartic Acid; Z-L-Aspartic Acid; (S)-2-(((Benzyloxy)carbonyl)amino)butanedioic Acid; N-Benzyloxycarbonyl-L-aspartic Acid; Cbz-Asp-OH; CBZ-L-Aspartic Acid; N-Carbobenzyloxy-L-aspartic Acid; L-Aspartic Acid, N-(phenylmethoxy)carbonyl]-
EINECS	214-560-3

Quality Control

Our n-Carbobenzyloxy-L-Aspartic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]²⁰D	-5.0° to -7.0° (c=1 in AcOH)
Chiral Purity (HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.