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Z-Gly-Gly-Oet CAS NO 1145-81-9


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CAS No.:1145-81-9

Grade:Pharmacy Grade

Content:99.0%

Brand:Customizable

Packaging:Customizable

Description

Z-Gly-Gly-Oet is a protected dipeptide derivative, specifically the ethyl ester of Z-protected glycylglycine. This compound serves as a crucial building block in peptide synthesis, offering a versatile intermediate for the controlled elongation of peptide chains. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biochemical sectors for developing novel therapeutic agents and conducting advanced proteomics research.

Application

  • Peptide Synthesis Intermediate: A fundamental building block in solid-phase and solution-phase peptide synthesis for constructing longer peptide sequences.
  • Pharmaceutical Research: Used in the research and development of new peptide-based drugs and active pharmaceutical ingredients (APIs).
  • Biochemical Tool: Employed in enzymatic studies and as a substrate or inhibitor model in protease research.
  • Academic Research: A standard reagent in university and institutional labs for teaching and investigating peptide chemistry principles.
  • Custom Peptide Production: Utilized by CROs and CDMOs for the custom synthesis of specific peptide sequences for clients.
  • Protecting Group Chemistry: Serves as a practical example and reagent in studies involving the Z (benzyloxycarbonyl) protecting group strategy.

Basic Information

Product Name Z-Gly-Gly-Oet
CAS No. 1145-81-9
Molecular Formula C₁₄H₁₈N₂O₅
Molecular Weight 294.30 g/mol
Synonyms N-Carbobenzoxy-glycylglycine ethyl ester; N-Cbz-Gly-Gly-OEt; Benzyloxycarbonyl-glycyl-glycine ethyl ester; Z-Gly-Gly-OEt; Nα-Carbobenzyloxy-glycylglycine ethyl ester; Glycine, N-[(phenylmethoxy)carbonyl]glycyl-, ethyl ester; Ethyl N-[(benzyloxy)carbonyl]glycylglycinate
EINECS 214-547-4

Quality Control

Our Z-Gly-Gly-Oet is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR), to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming batch-specific results for identity, purity, and related substances.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Melting Point 108 - 112 °C
Specific Rotation Contact for details
Heavy Metals < 10 ppm
Residue on Ignition < 0.1%
Water Content (KF) < 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.

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