Description

n-Carbobenzyloxyglycine is a protected amino acid derivative, specifically the N-carbobenzyloxy (Cbz) derivative of glycine. This compound serves as a crucial building block in organic synthesis, particularly in peptide chemistry, where it is used to introduce a glycine residue while protecting the amine functionality. It is primarily utilized by pharmaceutical intermediates manufacturers and research institutions involved in the development of peptides, peptidomimetics, and other bioactive molecules.

Application

• Peptide Synthesis: As a key protected glycine derivative for solid-phase and solution-phase peptide synthesis.
• Pharmaceutical Intermediates: In the production of active pharmaceutical ingredients (APIs) and drug candidates containing glycine motifs.
• Bioconjugation: For the chemical modification of proteins, antibodies, or other biomolecules.
• Research & Development: As a standard reagent in academic and industrial R&D labs for exploring new synthetic methodologies.
• Chemical Biology: In the synthesis of probes and tools for studying biological processes.
• Fine Chemical Production: As a precursor for more complex, high-value specialty chemicals.

Basic Information

Product Name	n-Carbobenzyloxyglycine
CAS No.	1138-80-3
Molecular Formula	C10H11NO4
Molecular Weight	209.20 g/mol
Synonyms	N-Carbobenzyloxyglycine; Cbz-Glycine; N-Cbz-Glycine; N-(Benzyloxycarbonyl)glycine; Glycine, N-[(phenylmethoxy)carbonyl]-; Z-Gly-OH; Benzyloxycarbonylglycine; NSC 3349
EINECS	214-524-9

Quality Control

Our n-Carbobenzyloxyglycine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets high-purity standards suitable for research and synthesis applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	118 - 122 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.