Description

3,4-Dihydroxyphenylacetamide is a high-purity catechol derivative with significant utility in advanced organic synthesis. This compound serves as a versatile and critical building block for the development of complex molecules, particularly in the pharmaceutical and fine chemical sectors. It is essential for researchers and manufacturers in medicinal chemistry, agrochemical development, and biochemical research who require a reliable, high-quality intermediate for synthesizing active pharmaceutical ingredients (APIs) and other specialty compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of catecholamine analogs, potential drug candidates for neurological and cardiovascular disorders.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving tyrosine hydroxylase or catechol-O-methyltransferase (COMT).
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and plant growth regulators that leverage the catechol moiety.
• Fine Chemical Production: Employed in the manufacture of dyes, pigments, and polymer stabilizers where the dihydroxy functionality is required.
• Antioxidant Research: Investigated for its radical scavenging properties in the development of cosmetic and nutritional antioxidant formulations.
• Chemical Reference Standard: Utilized as an analytical standard in quality control laboratories for HPLC, LC-MS, or NMR method development and validation.

Basic Information

Product Name	3,4-Dihydroxyphenylacetamide
CAS No.	1129-53-9
Molecular Formula	C8H9NO3
Molecular Weight	167.16 g/mol
Synonyms	3,4-Dihydroxybenzeneacetamide; 2-(3,4-Dihydroxyphenyl)acetamide; 3,4-Dihydroxyphenylethanamide; Homoprotocatechuamide; Catecholacetamide; DHPA; 1129-53-9 (CAS Registry Number)
EINECS	214-456-4

Quality Control

Our 3,4-Dihydroxyphenylacetamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability, consistency, and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.