Description

H-Glu(Oet)-Oh CAS NO 1119-33-1 is a protected derivative of the amino acid glutamic acid, specifically the ethyl ester of L-glutamic acid. This compound is a crucial building block in peptide synthesis, offering a protected carboxylic acid group that prevents unwanted side reactions during coupling steps. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel peptides and active pharmaceutical ingredients (APIs).

Application

• Peptide Synthesis: A fundamental building block (amino acid derivative) for solid-phase and solution-phase peptide synthesis.
• Pharmaceutical Intermediates: Serves as a key intermediate in the research and production of peptide-based therapeutics and drug candidates.
• Biochemical Research: Used in enzymatic studies, substrate preparation, and the investigation of metabolic pathways involving glutamic acid.
• Fine Chemical Production: Employed in the synthesis of complex organic molecules, chiral auxiliaries, and specialty chemicals.
• Protecting Group Chemistry: The ethyl ester group acts as a protective moiety for the γ-carboxyl function, which can be selectively deprotected as needed.

Basic Information

Product Name	H-Glu(Oet)-Oh
CAS No.	1119-33-1
Molecular Formula	C7H13NO4
Molecular Weight	175.18 g/mol
Synonyms	L-Glutamic acid 5-ethyl ester; L-Glutamic acid γ-ethyl ester; H-Glu(OEt)-OH; (S)-2-Amino-5-ethoxy-5-oxopentanoic acid; Ethyl L-glutamate; Ethyl hydrogen L-glutamate; Glutamic acid ethyl ester; 5-Ethyl L-glutamate
EINECS	214-276-4

Quality Control

Our H-Glu(Oet)-Oh is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, optical rotation for chiral integrity, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or manufacturing specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture, which can affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]20/D	+22.0° to +25.0° (c=1 in 1N HCl)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.