Description

Chloroacetyl-Dl-Isoleucine is a chemically modified amino acid derivative, specifically an N-chloroacetylated form of DL-isoleucine. This compound serves as a crucial building block (synthon) in organic synthesis and pharmaceutical research, enabling the controlled introduction of the isoleucine moiety into more complex molecular architectures. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries for developing novel peptides, prodrugs, and other bioactive compounds.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis as a protected amino acid derivative.
• Prodrug Development: Employed in the design and creation of prodrugs to enhance drug delivery and bioavailability.
• Bioconjugation: Acts as a linker or reagent for conjugating peptides to other molecules, such as polymers or fluorescent dyes.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and metabolic pathway investigations.
• Fine Chemical Synthesis: Intermediate for creating specialized chiral compounds and complex organic molecules.

Basic Information

Product Name	Chloroacetyl-Dl-Isoleucine
CAS No.	1115-24-8
Molecular Formula	C8H14ClNO3
Molecular Weight	207.66 g/mol
Synonyms	N-Chloroacetyl-DL-isoleucine; 2-Chloro-N-[(2S,3S)-1-hydroxy-3-methylpentan-2-yl]acetamide; DL-Isoleucine, N-chloroacetyl-; Chloroacetyl-DL-isoleucine; (RS)-2-(2-Chloroacetamido)-3-methylpentanoic acid; N-(2-Chloroacetyl)-DL-isoleucine; Acetamide, 2-chloro-N-(1-hydroxy-3-methyl-1-oxopentan-2-yl)-
EINECS	Contact for details

Quality Control

Our Chloroacetyl-Dl-Isoleucine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.