Description

Triflupromazine Hydrochloride is a high-purity phenothiazine derivative pharmaceutical intermediate. This compound is critical for the research, development, and production of antipsychotic medications, serving as a key building block for advanced therapeutic agents. It is primarily utilized by pharmaceutical manufacturers, research institutions, and fine chemical suppliers operating in the global life sciences sector.

Application

• Pharmaceutical Active Ingredient (API) Synthesis: Serves as a crucial intermediate in the manufacturing of triflupromazine-based antipsychotic drugs.
• Pharmacological Research: Used in preclinical and clinical studies to investigate the mechanisms and efficacy of phenothiazine-class compounds.
• Reference Standard: Employed as a certified reference material (CRM) in analytical laboratories for quality control and method validation.
• Process Development: Utilized in scaling up and optimizing synthetic routes for new chemical entities (NCEs) within the central nervous system (CNS) therapeutic area.
• Veterinary Medicine: Potential application in the formulation of tranquilizers for animal use.

Basic Information

Product Name	Triflupromazine Hydrochloride
CAS No.	1098-60-8
Molecular Formula	C18H19F3N2S • HCl
Molecular Weight	388.88 g/mol
Synonyms	10-[3-(Dimethylamino)propyl]-2-(trifluoromethyl)phenothiazine Hydrochloride; Triflupromazine HCl; Fluopromazine Hydrochloride; Vesprin Hydrochloride; Psyquil; Siquil; Adazine; Vetame; 2-Trifluoromethyl-10-(3-dimethylaminopropyl)phenothiazine Hydrochloride
EINECS	214-150-0

Quality Control

Our Triflupromazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and impurity profiles. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing results from tests such as HPLC assay, related substances, residual solvents, and heavy metals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water (KF Titration)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.