Description

Mandelamide, 3,4-Dihydroxy- (7Ci,8Ci) CAS NO 1078-51-9 is a specialized phenolic amide derivative of mandelic acid, serving as a key chiral building block and intermediate in advanced organic synthesis. Its catechol structure provides unique reactivity, making it valuable for constructing complex molecules with specific stereochemistry and functional groups. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for developing active pharmaceutical ingredients (APIs) and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A crucial chiral precursor in the synthesis of potential drug candidates, particularly those targeting neurological and cardiovascular systems.
• Fine Chemical Synthesis: Used as a building block for creating complex ligands, catalysts, and specialty polymers requiring a catechol moiety.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies, especially those involving tyrosine hydroxylase or catechol-O-methyltransferase (COMT).
• Asymmetric Synthesis: Exploited for its chiral center in the preparation of enantiomerically pure compounds for agrochemicals and advanced materials.
• Chelating Agent Precursor: Its vicinal dihydroxy (catechol) structure makes it a starting material for synthesizing metal-chelating agents.

Basic Information

Product Name	Mandelamide, 3,4-Dihydroxy- (7Ci,8Ci)
CAS No.	1078-51-9
Molecular Formula	C9H11NO4
Molecular Weight	197.19 g/mol
Synonyms	3,4-Dihydroxymandelamide; 2-(3,4-Dihydroxyphenyl)-2-hydroxyacetamide; 3,4-Dihydroxy-α-hydroxybenzeneacetamide; (R/S)-3,4-Dihydroxymandelamide; DL-3,4-Dihydroxymandelamide; Catecholmandelamide; 2-Hydroxy-2-(3,4-dihydroxyphenyl)acetamide
EINECS	214-100-9

Quality Control

We maintain stringent quality control protocols for our fine chemical intermediates. Each batch of Mandelamide, 3,4-Dihydroxy- is analyzed to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing parameters such as assay, chiral purity (if applicable), and impurity profiles. Our quality system is designed to support cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from strong oxidizing agents. For long-term storage, consider packaging under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.