Description

D-Glutamic Acid Diethyl Ester Hydrochloride is a high-purity chiral building block and protected amino acid derivative essential for advanced organic synthesis. This compound is valued for its role in the stereoselective construction of peptides and peptidomimetics, where the D-configuration and ester protection are critical. It serves as a key intermediate for researchers and manufacturers in pharmaceutical development, particularly in creating novel active pharmaceutical ingredients (APIs) and investigating metabolic pathways.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and production of peptide-based drugs and bioactive molecules.
• Biochemical Research: Used in enzymatic studies and as a substrate or inhibitor in metabolic pathway investigations.
• Asymmetric Synthesis: Serves as a building block for the preparation of non-proteinogenic amino acids and complex natural products.
• Protecting Group Chemistry: The diethyl ester group provides temporary protection for the carboxylic acid functionality during multi-step synthetic sequences.
• Neuroscience Research: Potential use in studies related to glutamate receptors and neurotransmission due to its structural similarity to glutamic acid.

Basic Information

Product Name	D-Glutamic Acid Diethyl Ester Hydrochloride
CAS No.	1001-19-0
Molecular Formula	C9H18ClNO4
Molecular Weight	239.70 g/mol
Synonyms	D-Glutamic Acid Diethyl Ester HCl; Diethyl D-glutamate hydrochloride; (R)-2-Aminopentanedioic Acid Diethyl Ester Hydrochloride; H-D-Glu(OEt)-OEt·HCl; D-Glutamic Acid Diethyl Ester Hydrochloride Salt; D-Glutamic Acid Diethyl Ester Monohydrochloride; D-Glutamic Acid Diethyl Ester HCl Salt
EINECS	Contact for details

Quality Control

Our D-Glutamic Acid Diethyl Ester Hydrochloride is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical and research applications. A Certificate of Analysis (COA) detailing identity, purity, and specific impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.