Description

2-Amino-4,4'-Dichlorodiphenyl Ether is a high-purity organic intermediate characterized by its aromatic ether structure with amine and chloro substituents. This compound is valued for its role as a versatile building block in the synthesis of more complex chemical entities, particularly in advanced material science. It is primarily sought after by manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries for research and development as well as scale-up production.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a diphenyl ether backbone.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and insecticides, where its dichloro and amino groups contribute to biological activity.
• Polymer & Resin Modifier: Serves as a monomer or additive in the production of high-performance polymers, epoxy resins, and polyimides to enhance thermal stability and chemical resistance.
• Dye & Pigment Manufacturing: Acts as an intermediate in the synthesis of complex organic dyes and pigments, especially azo dyes.
• Liquid Crystal & OLED Materials: Employed in the research and development of electronic display materials due to its rigid, planar molecular structure.
• Cross-coupling Reactions: A valuable substrate in palladium-catalyzed reactions like Buchwald-Hartwig amination for creating carbon-nitrogen bonds.

Basic Information

Product Name	2-Amino-4,4'-Dichlorodiphenyl Ether
CAS No.	121-27-7
Molecular Formula	C12H9Cl2NO
Molecular Weight	254.11 g/mol
Synonyms	4,4'-Dichloro-2-aminodiphenyl Ether; 2-Amino-4,4'-dichlorodiphenyl Oxide; 4-Amino-2,4'-dichlorodiphenyl Ether; 4,4'-Dichloro-2-anilinodiphenyl Ether; Bis(4-chlorophenyl) Ether-2-amine; 2-AADPE; 2-ADPE; 121-27-7
EINECS	204-458-8

Quality Control

Our 2-Amino-4,4'-Dichlorodiphenyl Ether is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and spectroscopic identification (IR, NMR). We provide a Certificate of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your internal quality standards and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. The product may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.