Antiarrhythmics
Circulatory System Drugs
- Lipid Regulators
- Antianginals
- Calcium Channel Blockers
- Anticongestive Heart Failure Drugs
- Antihypertensives
- Antiarrhythmics
- Shock Vasoactive Drugs
- Other Cardiovascular Drugs
- ACE Inhibitors and ARBs
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- β-Adrenergic Receptor Blockers
- Chronic Heart Failure Therapeutics
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Antiarrhythmics
Antiarrhythmic drugs are therapeutic agents used to restore normal cardiac rhythm, suppress abnormal electrical activity, and prevent arrhythmia recurrence. They are categorized into Vaughan–Williams classes I through IV, based on their primary electrophysiological mechanisms: sodium channel blockers, β-blockers, potassium channel blockers, and calcium channel blockers. Additional agents such as adenosine and digoxin exert specialized effects on nodal conduction. Antiarrhythmics treat conditions including atrial fibrillation, atrial flutter, supraventricular tachycardia, ventricular tachycardia, and premature beats. Their mechanisms involve modifying ion fluxes, prolonging refractory periods, slowing conduction velocity, or inhibiting aberrant pacemaker activity. Because some drugs may induce proarrhythmia, therapy requires individualized selection and ECG monitoring. Antiarrhythmics remain indispensable in acute care and long-term rhythm management.
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