Antiatherosclerotic Drugs
Circulatory System Drugs
- Lipid Regulators
- Antianginals
- Calcium Channel Blockers
- Anticongestive Heart Failure Drugs
- Antihypertensives
- Antiarrhythmics
- Shock Vasoactive Drugs
- Other Cardiovascular Drugs
- ACE Inhibitors and ARBs
- Peripheral Vasodilators
- β-Adrenergic Receptor Blockers
- Chronic Heart Failure Therapeutics
- Antiatherosclerotic Drugs
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Antiatherosclerotic Drugs
Antiatherosclerotic drugs target the underlying mechanisms of plaque formation, inflammation, endothelial dysfunction, and lipid oxidation that contribute to atherosclerosis progression. Core therapeutic classes include statins, PCSK9 inhibitors, ezetimibe, omega-3 fatty acids, fibrates, and antioxidants. Statins remain first-line therapy due to their potent LDL-lowering effects and ability to stabilize plaques. PCSK9 inhibitors offer profound lipid reduction, particularly in familial hypercholesterolemia. Anti-inflammatory agents, including colchicine, have shown benefit in reducing cardiovascular events by modulating vascular inflammation. These medications are used in coronary artery disease, peripheral artery disease, carotid stenosis, and long-term prevention of myocardial infarction and stroke. Antiatherosclerotic therapy is essential for reducing morbidity and mortality associated with atherosclerotic cardiovascular disease.
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