Tinib Antineoplastic Drugs

Tinib Antineoplastic Drugs

Tinib antineoplastic drugs are a major class of targeted cancer therapies that inhibit dysregulated tyrosine kinases or serine/threonine kinases involved in tumor growth, angiogenesis, and metastasis. Represented by imatinib, erlotinib, gefitinib, sunitinib, sorafenib, and numerous next-generation inhibitors, these APIs block oncogenic signaling pathways such as EGFR, VEGFR, PDGFR, BCR-ABL, ALK, and RET. Their precision targeting enables high efficacy with reduced systemic toxicity compared to traditional chemotherapy. Tinib drugs are widely used in leukemia, lung cancer, renal cancer, gastrointestinal stromal tumors, and melanoma. Resistance caused by kinase mutations has led to the development of multi-targeted and mutation-specific inhibitors, making tinibs a cornerstone of precision oncology.

Marimastat CAS NO 154039-60-8

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1-[(2R)-4-[5-[(4-Fluorophenyl)Methyl]Thiophen-2-Yl]But-3-Yn-2-Yl]-1-Hydroxy-Urea CAS NO 154355-76-7

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Noto CAS NO 155256-95-4

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CAS No.:155256-95-4

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Cpi-975 CAS NO 157244-53-6

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CAS No.:157244-53-6

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Perifosine (Krx-0401) CAS NO 157716-52-4

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CAS No.:157716-52-4

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Nsc670365 CAS NO 161753-49-7

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Temsirolimus Acetonide CAS NO 162635-03-2

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CAS No.:162635-03-2

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Temsirolimus CAS NO 162635-04-3

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CAS No.:162635-04-3

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