Description

Erlotinib Hydrochloride CAS NO 183321-69-9 is a small molecule tyrosine kinase inhibitor that selectively targets the epidermal growth factor receptor (EGFR). This compound is of critical importance in the development and production of targeted cancer therapeutics. It is primarily required by pharmaceutical manufacturers and research institutions engaged in oncology drug development, formulation, and clinical studies.

Application

• Active Pharmaceutical Ingredient (API) in the manufacture of targeted cancer therapy drugs.
• Reference Standard for quality control and analytical method development in pharmaceutical laboratories.
• Biochemical Research for studying EGFR signaling pathways and mechanisms of drug resistance.
• Formulation Development for creating various dosage forms such as tablets or capsules.
• Pre-clinical and Clinical Research material for pharmacological and toxicological studies.

Basic Information

Product Name	Erlotinib Hydrochloride
CAS No.	183321-69-9
Molecular Formula	C22H23N3O4 • HCl
Molecular Weight	429.90 g/mol (free base: 393.44 g/mol)
Synonyms	Erlotinib HCl; N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine hydrochloride; OSI-774; CP-358774; Tarceva (brand name); NSC 718781; 4-Quinazolinamine, N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our Erlotinib Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and strength, meeting high-grade pharmaceutical standards. A Certificate of Analysis (COA) detailing specifications such as assay, related substances, residual solvents, and microbiological quality is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time conforms to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm
Sulfated Ash	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.