Description

Erlotinib is a potent and selective small-molecule inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase. This targeted therapeutic agent is critical for disrupting the signaling pathways that drive the proliferation and survival of certain cancer cells. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of oncology medications, particularly for the treatment of non-small cell lung cancer (NSCLC) and pancreatic cancer.

Application

• Active Pharmaceutical Ingredient (API) in the manufacture of targeted cancer therapeutics.
• Key intermediate in advanced pharmaceutical research and development for EGFR-mutated cancers.
• Reference standard for quality control and analytical testing in pharmaceutical laboratories.
• Biochemical research tool for studying EGFR signaling pathways and mechanisms of drug resistance.
• Preclinical development of novel combination therapies in oncology.

Basic Information

Product Name	Erlotinib
CAS No.	183320-72-1
Molecular Formula	C22H23N3O4
Molecular Weight	393.44 g/mol
Synonyms	N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine; CP-358774; OSI-774; Tarceva (Trade Name); NSC 718781; Erlotinib Hydrochloride (Salt Form); EGFR Tyrosine Kinase Inhibitor
EINECS	Contact for details

Quality Control

Our Erlotinib is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and the absence of specified impurities. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are kept sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.