Description

Erlotinib is a potent and selective small-molecule inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase. This targeted therapeutic agent is critical for disrupting the signaling pathways that drive uncontrolled cell proliferation in certain cancers. It is primarily required by pharmaceutical manufacturers and research institutions engaged in oncology drug development and production.

Application

• Active Pharmaceutical Ingredient (API): Core component in the formulation of finished anti-cancer medications.
• Oncology Research: Used as a reference standard and investigational tool in preclinical and clinical studies targeting EGFR mutations.
• Pharmaceutical Intermediates: Serves as a key intermediate in the synthesis of more complex targeted therapies.
• Biochemical Assay Development: Employed in high-throughput screening and assay validation for drug discovery platforms.
• Academic Research: Utilized in university and institutional labs for studying tyrosine kinase inhibitor mechanisms and resistance.

Basic Information

Product Name	Erlotinib
CAS No.	183321-74-6
Molecular Formula	C22H23N3O4
Molecular Weight	393.44 g/mol
Synonyms	N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine; CP-358774; OSI-774; Tarceva (Trade Name); NSC 718781; Erlotinib Hydrochloride (Salt Form); EGFR Tyrosine Kinase Inhibitor; 6,7-Bis(2-methoxyethoxy)quinazolin-4-yl-(3-ethynylphenyl)amine
EINECS	Contact for details

Quality Control

Our Erlotinib is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling via HPLC, to ensure it meets stringent pharmaceutical-grade specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.