Alkylating Antineoplastic Agents

Antineoplastics

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Alkylating Antineoplastic Agents

Alkylating antineoplastic agents are cytotoxic APIs that form covalent bonds with DNA, leading to cross-linking, strand breaks, and inhibition of replication and transcription. This class includes nitrogen mustards, nitrosoureas, alkyl sulfonates, triazenes, and platinum-based drugs. They are effective against a wide range of hematologic malignancies and solid tumors such as breast cancer, ovarian cancer, sarcomas, and brain tumors. Their mechanism is cell cycle–nonspecific, making them particularly active against rapidly dividing cells. However, their strong cytotoxicity can result in bone marrow suppression, infertility, and secondary malignancies. Despite these risks, alkylating agents remain foundational drugs in many chemotherapeutic regimens due to their broad antitumor activity.

Ambamustine CAS NO 85754-59-2

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CAS No.:85754-59-2

Grade:Pharmacy Grade

Content:99.90%

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1,3-Dipalmitoyl-2-(4-(Bis(2-Chloroethyl)Amino)Benzenebutanoyl)Glycerol CAS NO 85763-07-1

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CAS No.:85763-07-1

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Tauromustine CAS NO 85977-49-7

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CAS No.:85977-49-7

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N(Sup 2)-(((2-Chloroethyl)Nitrosoamino)Carbonyl)-L-Lysyl-L-Prolyl-L-Va Linamide Hydrochloride CAS NO 87230-64-6

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CAS No.:87230-64-6

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5-[Bis-(2-Chloroethyl)Amino]-1-Methyl-1H-Benzimidazole-2-Butanoic Acid Ethyl Ester CAS NO 87475-54-5

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CAS No.:87475-54-5

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n-(2-Chloroethyl)-n-Nitrosocarbamoyl-Omega-Lysine CAS NO 87494-15-3

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CAS No.:87494-15-3

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17-Aza-Homo-Delta (1,3,5(10)) Estratrien-3-Ol-17-One-4-N,n-Bis(2-Chloroethyl)Aminophenylacetate CAS NO 87777-66-0

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CAS No.:87777-66-0

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Mafosfamide Cyclohexylamine Salt CAS NO 88746-71-8

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CAS No.:88746-71-8

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