Description

Tauromustine is a synthetic alkylating agent belonging to the nitrosourea class of compounds. This specialized chemical is of significant interest in pharmaceutical research and development due to its mechanism of action. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly in the field of oncology.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or active pharmaceutical ingredient (API) in preclinical and clinical research for novel cancer therapies.
• Oncology Drug Discovery: Used in the synthesis and study of new alkylating chemotherapeutic agents targeting various cancer cell lines.
• Biochemical Research: Employed as a tool compound in laboratories to study DNA alkylation, cross-linking mechanisms, and cellular apoptosis pathways.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in pharmaceutical analysis (HPLC, LC-MS).
• Academic Studies: Utilized in university and institutional research projects investigating the structure-activity relationships (SAR) of nitrosourea derivatives.

Basic Information

Product Name	Tauromustine
CAS No.	85977-49-7
Molecular Formula	C₆H₁₂N₄O₄
Molecular Weight	204.18 g/mol
Synonyms	TCNU; Tauromustine; 1-(2-Chloroethyl)-3-[2-(dimethylaminosulfonyl)ethyl]-1-nitrosourea; 1-(2-Chloroethyl)-3-[2-[(dimethylamino)sulfonyl]ethyl]-1-nitrosourea; NSC 356610; CNCC 1102
EINECS	Contact for details

Quality Control

Our Tauromustine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including identification, assay, and impurity profiling. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with our rigorous in-house specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). For long-term storage, consider keeping the material at 2-8°C. The container should be kept in a well-ventilated area and handled with appropriate personal protective equipment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.