Description

17-Aza-Homo-Delta (1,3,5(10)) Estratrien-3-Ol-17-One-4-N,n-Bis(2-Chloroethyl)Aminophenylacetate is a sophisticated, high-purity synthetic steroid derivative with a nitrogen mustard moiety. This compound is valued for its role as a critical pharmaceutical intermediate in advanced research and development, particularly in the synthesis of targeted therapeutic agents. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in oncology and endocrinology research.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel steroid-based therapeutic compounds.
• Oncological Research: Used in the development of experimental chemotherapeutic agents due to its nitrogen mustard functional group.
• Endocrine System Studies: Serves as a precursor or reference standard in hormonal pathway and receptor interaction research.
• Biochemical Tool Compound: Employed in academic and industrial laboratories to study enzyme inhibition or steroid metabolism.
• Advanced Organic Synthesis: Utilized by medicinal chemists for structure-activity relationship (SAR) studies and molecular design.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Item	Detail
Product Name	17-Aza-Homo-Delta (1,3,5(10)) Estratrien-3-Ol-17-One-4-N,n-Bis(2-Chloroethyl)Aminophenylacetate
CAS No.	87777-66-0
Molecular Formula	C30H37Cl2N2O3
Molecular Weight	544.54 g/mol
Synonyms	4-[Bis(2-chloroethyl)amino]phenyl 17-Aza-D-homo-1,3,5(10)-estratriene-3,17a-diol-17-one Acetate; Estramustine Impurity; 17-Aza-D-homoestra-1,3,5(10)-triene-3,17a-diol-17-one 4-[Bis(2-chloroethyl)amino]phenyl Acetate; NSC 330500; 17-Aza-D-homoestratrienolone Mustard Phenylacetate; Aza-Homoestratrienolone Nitrogen Mustard Ester
EINECS	Contact for details

Quality Control

Our production of 17-Aza-Homo-Delta (1,3,5(10)) Estratrien-3-Ol-17-One-4-N,n-Bis(2-Chloroethyl)Aminophenylacetate adheres to stringent quality protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets exacting research-grade specifications. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation and ensure long-term stability. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.